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Compliance and Outcome of Osteoporosis Treatment After Total Knee Arthroplasty

Compliance and Outcome of Osteoporosis Treatment After Total Knee Arthroplasty

Yun Seong Choi, MD, KOREA, REPUBLIC OF Seung Hoon Lee, MD, KOREA, REPUBLIC OF Jung Ro Yoon, MD, KOREA, REPUBLIC OF Young Bin Shin, MD, KOREA, REPUBLIC OF Tae Hyuk Yoon, MD, KOREA, REPUBLIC OF

Veterans Health Service Medical Center, Seoul, KOREA, REPUBLIC OF


2023 Congress   ePoster Presentation   2023 Congress   Not yet rated

 

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Summary: Osteoporosis treatment compliance was significantly higher in the total knee arthroplasty group than in the out-patients clinic group and treatment outcome was comparable.


Background

Treatment compliance is important in the treatment of osteoporosis. Our hypotheses were as follows: 1) compliance with osteoporosis treatment after total knee arthroplasty (TKA) will be high, and 2) osteoporosis treatment results after TKA will be as good as those of patients who do not undergo TKA.

Methods

and Materials: Patients diagnosed with osteoporosis for the first time in an outpatient clinic (OPD group) and those who were diagnosed at hospitalization for TKA (TKA group) from March 2019 to December 2020 were retrospectively evaluated. Only patients treated with denoxumab were included in the study. Compliance, based on the outpatient follow-up rate after 1 year, was compared between the two groups, and the treatment outcomes were compared based on bone mineral density (BMD).

Results

In the OPD group, 29 of 41 patients were followed up 1 year later, and in the TKA group, all 26 patients were followed up after 1 year. In the OPD group, the BMD increased significantly. In the TKA group, there was a significant increase in BMD only in the lumbar spine. However, there were no significant between-group differences in the BMD before and after treatment.

Conclusion

Osteoporosis treatment compliance was significantly higher in the TKA group than in the OPD group. When denoxumab was used after TKA, there was no decrease in BMD, and osteoporosis treatment results after TKA were similar to those of the OPD group.


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