2023 ISAKOS Biennial Congress ePoster
Central Sensitization is Associated with Persistent Postoperative Pain and Inferior Patient-Reported Outcomes in Patients Undergoing Unicompartmental Knee Arthroplasty
Yong In, MD, PhD, Seoul KOREA, REPUBLIC OF
Dongho Kwak, MD, Seoul KOREA, REPUBLIC OF
Sungcheol Yang, MD, Seoul KOREA, REPUBLIC OF
Hyukjin Jang, MD, Seoul KOREA, REPUBLIC OF
Ryu Kyoung Cho, MD, Seoul KOREA, REPUBLIC OF
Man-Soo Kim, MD, PhD, Seoul KOREA, REPUBLIC OF
The Catholic University of Korea Seoul ST. MARY`s Hospital, Seoul, KOREA, REPUBLIC OF
FDA Status Cleared
Summary
CS(Central Sensitization) is an associated factor for persistent postoperative pain and greater knee joint awareness in patients undergoing UKA.
ePosters will be available shortly before Congress
Abstract
Central Sensitization is associated with Persistent Postoperative Pain and Inferior Patient-Reported Outcomes in Patients Undergoing Unicompartmental Knee Arthroplasty
Background
It is well known that central sensitization (CS) has a close relationship with persistent pain and inferior patient-reported outcome measures (PROMs) after total knee arthroplasty (TKA). However, studies on the relationship between CS and PROMs including postoperative pain are still lacking in patients undergoing unicompartmental knee arthroplasty (UKA). Therefore, the purpose of this study was to investigate whether CS was associated with postoperative pain and PROMs after UKA.
Methods
Between 2014 and 2019, 122 cases (122 patients) of UKA performed by a single surgeon were included in this study with a minimum follow-up of two years. CS was evaluated preoperatively using a Central Sensitization Inventory (CSI). Based on the CSI score of 40, it was divided into CS and non-CS groups. There were 96 patients (78.7%) in non-CS group, while the CS group consisted of 26 patients (21.3%). PROMs were also evaluated by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and forgotten joint score (FJS).
Results
The CSI score of the CS group was 45, and the average of the non-CS group was 22. The preoperative WOMAC pain, function and total score were significantly worse in the CS group than in the non-CS group (Pain: 18.4 vs 15.8, Function 46.0 vs 36.2, Total: 69.9 vs 56.0, all p < 0.05). This trend continued at 2 years after surgery (Pain: 3.4 vs 1.6, Function 14.8 vs 8.8, Total: 19.6 vs 11.4, all p < 0.05). FJS at 2 years after surgery was also significantly lower in the CS group than in the non-CS group (64.4 vs 72.8, p < 0.05).
Conclusion
CS is an associated factor for persistent postoperative pain and greater knee joint awareness in patients undergoing UKA.