2015 ISAKOS Biennial Congress ePoster #2614

Uric Acid Screening in Runners During Warsaw Marathon 2012

Mateusz Janik, MD, Warszawa POLAND
Ewa Wiesik-Szewczyk, MD, Warszawa POLAND
Robert Smigielski, MD, PhD, Warsaw, masovian POLAND
Daniel Kopko, MD, Warszawa, Warszawa POLAND

Carolina Medical Center, Warsaw, POLAND

FDA Status Not Applicable

Summary: The study was performed to assess uric acid level in marathon runners and provide the analysis of its relationship to existing co-morbidities, history of joints and muscle injury, and marathon results.




Hyperurycaemia is a risk factor of coronary artery diseases, metabolic syndrome and musculoskeletal disorders. In patients with hyperurycaemia systematic physical activity is recommended. The relationship between uric acid levels and physical exercise is not yet established. Objectives: The aim of our study was to assessof uric acid level in marathon runners and to provide the analysis of its relationship to co-morbidities, history of joints and muscle injury and marathon results. Methods: The blood uric acid levels were measured with a portable electrochemical uric acid measure (UA sure)1with the use of one drop from finger capillaries according to instruction provided by the producer and previously published data. Assessment was performed at the start and the end of the race. Gender, age, weight (before and up to 60 min after running), fluids and food intake during the run were recorded. Moreover, participants were asked about history of contusions, chronic illness, medication, and problems during the run. All participants provided self-assessment of the post-race satisfaction in 4 grades scale (1- very unsatisfied, 4- very satisfied). We used T student test for statistical analysis. Results: Among consecutively invited runners, 52 agreed to participate (4 female), mean age was 41 years (age range: 25-68). The premarathon uric acid level was 6,08 mg% (SD=1,37) and the postmarathon 8,17 mg% (SD=1,98).. Average uric acid level increase was 2.08mg% (SD=1,83mg%, P<0,05). The mean body mass was 78,6kg (SD=11,33). Average body mass weight loss was 1.46 kg (SD=1,64kg, P<0,05). Most of the participations (n=32) were very satisfied with their outcome. None of the subject experienced any adverse medical events. We noticed that runner how complain on cramps during the race have higher increase of uric acid then rest of respondents (3,99mg% to 2,11mg%). We did not found any correlation of uric acid level with analyzed factors as: weight , running outcome, joints injury. Conclusions: Exhaustive physical training increased serum uric acid level. The change of uric acid level was independent of dehydration and did not correlate with race result or joints injury. The significance of hyperurycaemia in extensive runners remains to be established.