2015 ISAKOS Biennial Congress ePoster #1417

Evaluation of a Cementless Hydroxyapatite-Coated Total Knee Implant Prospective Study of Eigthy-Four Patients With Eight Years Follow Up

Jean Louis Pincon, MD, Vichy FRANCE
Jean-Marie Ragot, MD, Voiron FRANCE
Xavier Normand, , Chamalieres, FRANCE

Clinic pergola vichy , vichy , FRANCE

The FDA has not cleared the following pharmaceuticals and/or medical device for the use described in this presentation. The following pharmaceuticals and/or medical device are being discussed for an off-label use:

Summary: According to the data collected in this study, the cementless total knee arthroplasty met our expectations in terms of survival and optimal bone fixation after 8 years



One of the main factors affecting the survival
of a total knee arthroplasty (TKA) is the fixation method.
The constraints placed on the bone–implant interface of a
mobile-bearing TKA must be taken in account during the
design and evaluation phases. For more than two decades,
calcium phosphate ceramics, particularly hydroxyapatitis,
have been used in Europe to accelerate the bone integration
of cementless implants. A prospective study of patients
continuously recruited by senior surgeons at
private hospitals has been carried out. There were
no exclusion criteria. Eighty-four (84) cementless mobile bearing
total knee prosthesis were implanted in 74 patients over a 2-year period
(2004–2005). Implant survival at 8 years was 95 % [with a
confidence interval of 95 %: 80.2–96.4 %] when revision
for any cause was defined as the endpoint. Five implants
required surgical revision to exchange all or part of the
implant: two for aseptic loosening of tibial component, one
for osteolysis, one for persistent flessum (30_) and one for
tibial periprosthetic fracture. Completely integrated
implants and event-free outcomes were recorded in 91.4 %
of the cases at eight-year follow-up. The Hospital for
Special Surgery score significantly improved from 56.8/
100 points before the surgery to 83.9/100 points at the last
follow-up (p\0.05). This cementless total knee prosthesis yielded good medium-
term survival. Cementless arthroplasty can generate
solid and durable bone fixation in this total weight-bearing
implant, and it seems that the hidroxyapathitis surface in
this series stimulate the bone integration at the bone–
implant interface