2015 ISAKOS Biennial Congress ePoster #1205
Autograft Soaking in Vancomycin Reduces the Risk of Infection After Anterior Cruciate Ligament Reconstruction.
Daniel Pérez-Prieto, MD, Barcelona SPAIN
Raúl Torres-Claramunt, PhD, Barcelona SPAIN
Pablo E. Gelber, MD, PhD, Barcelona SPAIN
Tamer Shehata, FELLOW OF EUROPEAN BOARD OF ORTHO AND TRAUMATOLOGY, Khobar, EASTERN SAUDI ARABIA
Xavier Pelfort, PhD, Igualada SPAIN
Joan C. Monllau, MD, PhD, Prof., Barcelona SPAIN
Parc de Salut Mar, Barcelona, SPAIN
FDA Status Cleared
Summary: Autograft soaking in vancomycin reduces the risk of infection after anterior cruciate ligament reconstruction.
To determine whether an anterior cruciate ligament (ACL) autograft bathed in vancomycin reduces the rate of infection following an ACL reconstruction.
Retrospective analysis of all ACL reconstructions over an 8 year period in 2 University Hospitals. In the initial 4-year period, all patients were operated on under classical antibiotic intravenous prophylaxis (Group 1). Over the last 4-year period, this prophylaxis was supplemented with presoaking of the autograft (Group 2). Presoaking was performed with sterile gauze previously saturated with a vancomycin solution (5 mg/ml).
There were 810 and 734 patients in group 1 and 2, respectively. Fifteen cases of knee joint infections were identified in the series (0.97%). All of these infections occurred in group 1, representing a rate of infection of 1.8% in comparison with 0% in group 2 (p=0.002).
Autograft presoaking with vancomycin in combination with classical intravenous antibiotic prophylaxis reduced the rate of knee joint infection following an ACLR in comparison to antibiotic prophylaxis alone.