Explore the evolution of Platelet-Rich Plasma (PRP) therapy, from its early applications to current evidence-based practices, and discuss future advancements in regenerative medicine.

• Historical Perspective & Mechanisms of Action: Review the origins of PRP, its biological basis, and how its mechanisms influence healing in musculoskeletal and sports injuries. • Current Clinical Applications & Evidence: Analyse the latest research, clinical guidelines, and controversies surrounding PRP use in orthopaedics, sports medicine, and beyond. • Future Innovations & Challenges: Discuss advancements in PRP formulations, delivery methods, and combination therapies, along with challenges in standardization and regulatory approval.