2017 ISAKOS Biennial Congress ePoster #1027
Analgesic Effect of Intra-Articular Ropivacaine-Morphine in Comparison with Ropivacaine-Clonidine Combination and Normal Saline Only in ACL Reconstruction Patients on Post-Operative Pain
Shekhar Srivastav, MS(Orth), Delhi INDIA
Amit Srivastava, MS orthopedics, Delhi INDIA
Harjoban Singh, DO,DNB,MBBS, New Delhi, India INDIA
Sant Parmanand Hospital,, New Delhi, Delhi, INDIA
The FDA has not cleared the following pharmaceuticals and/or medical device for the use described in this presentation. The following pharmaceuticals and/or medical device are being discussed for an off-label use:
Summary
This study compares the efficacy of intra-articular administration of Ropivacaine-morphine combination in compression with Ropivacaine -Clonidine combination and Normal saline only on the post operative pain in ACL reconstructed patients
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Abstract
Background
Arthroscopic ACL reconstruction surgery is commonly performed as an outpatient procedure and is often associated with postoperative pain.
Objectives: We aimed to compare the effects of intra-articular ropivacaine-clonidine, ropivacaine-morphine on postoperative pain in patients undergoing elective arthroscopic ACL reconstruction surgery.
Materials And Methods
A total of 60 patients undergoing elective arthroscopic ACL reconstruction under spinal anaesthesia were enrolled. The participants were allocated to three groups to receive the following intra-articular medications after completion of the surgery and before deflation of the tourniquet: Group I, 20 mL of saline; Group II , 0.25% Ropivacaine with 75 µg Clonidine in 20 mL saline; and Group III,0 .25% Ropivacaine and 5 mg morphine in 20 mL saline. Visual analogue scale (VAS) values were recorded at 1, 2, 4, 8 and 12 hours postoperatively, duration of analgesia, total analgesic consumption, and number of rescue analgesia at 24 hours were evaluated.
Results
VAS was significantly higher in group I in comparison to other groups. Duration of analgesia was significantly longer in Group II and Group III than in Group I. Number of rescue analgesia and total analgesic consumption at postoperative hour 24 was significantly fewer in group III compared with other groups.
Conclusions
Intraarticular ropivacaine-morphine combination provides effective pain relief, longer analgesic duration, and less analgesic requirement when compared with intra-articular ropivacaine-cloinidine combination and saline after arthroscopic ACL reconstruction surgery.