2015 ISAKOS Biennial Congress ePoster #1205

Autograft Soaking in Vancomycin Reduces the Risk of Infection After Anterior Cruciate Ligament Reconstruction.

Daniel Pérez-Prieto, MD, Barcelona SPAIN
Raúl Torres-Claramunt, PhD, Barcelona SPAIN
Pablo E. Gelber, MD, PhD, Barcelona SPAIN
Tamer Shehata, FELLOW OF EUROPEAN BOARD OF ORTHO AND TRAUMATOLOGY, Khobar, EASTERN SAUDI ARABIA
Xavier Pelfort, PhD, Igualada SPAIN
Joan C. Monllau, MD, PhD, Prof., Barcelona SPAIN

Parc de Salut Mar, Barcelona, SPAIN

FDA Status Cleared

Summary: Autograft soaking in vancomycin reduces the risk of infection after anterior cruciate ligament reconstruction.

Rate:

Abstract:

Purpose

To determine whether an anterior cruciate ligament (ACL) autograft bathed in vancomycin reduces the rate of infection following an ACL reconstruction.

Methods

Retrospective analysis of all ACL reconstructions over an 8 year period in 2 University Hospitals. In the initial 4-year period, all patients were operated on under classical antibiotic intravenous prophylaxis (Group 1). Over the last 4-year period, this prophylaxis was supplemented with presoaking of the autograft (Group 2). Presoaking was performed with sterile gauze previously saturated with a vancomycin solution (5 mg/ml).

Results

There were 810 and 734 patients in group 1 and 2, respectively. Fifteen cases of knee joint infections were identified in the series (0.97%). All of these infections occurred in group 1, representing a rate of infection of 1.8% in comparison with 0% in group 2 (p=0.002).

Conclusions

Autograft presoaking with vancomycin in combination with classical intravenous antibiotic prophylaxis reduced the rate of knee joint infection following an ACLR in comparison to antibiotic prophylaxis alone.