2015 ISAKOS Biennial Congress Paper #0

Subacromial Platelet Rich Plasma Injections For Rotator Cuff Tendinopathy Are Partial Thickness Tears Associated With Poor Functional Outcomes?

Luciano Rossi, PhD, Buenos Aires ARGENTINA
Rodrigo Nicolás Brandariz, MD, San isidro, Buenos Aires ARGENTINA
Ignacio Tanoira, MD PhD, Buenos Aires ARGENTINA
Nicolás Piuzzi, MD, Cleveland, OHIO UNITED STATES
Maximiliano Ranalletta, MD, Buenos Aires, Buenos Aires ARGENTINA
Hospital Italiano de Buenos Aires, Ciudad de Buenos Aires, Buenos Aires, ARGENTINA

FDA Status Cleared

Summary: Improvement in symptoms and functional outcomes after PRP subacromial injections were significantly worse in patients who had a Partial thickness rotator cuff tears compared with patients who had an isolated tendinopathy.

Abstract:

Purpose

The purpose of this study was to compare the effect of subacromial leukocyte-rich PRP injections in patients with isolated rotator cuff tendinopathy (RCT) and those with partial thickness rotator cuff tears (PTRCTs) based on functional outcomes, pain improvement, sleep disturbances, and return to sports.

Materials And Methods

Between November 2019 and March 2021, 150 patients underwent PRP injections in our institution for refractory rotator cuff tendinopathy (105 RCTs and 45 PTRCTs). The American Shoulder and Elbow Surgeons (ASES) score, The visual analog scale (VAS) for pain, the Single Assessment Numeric Evaluation (SANE) and The Pittsburgh Sleep Quality Index were evaluated at 2, 6 and 12 month follow up. Return to sports was also evaluated. An ultrasound examination was performed to evaluate structural outcomes 12 months after the injection.

Results

The mean age was 36.6 years (±9.08). Overall, the ASES, VAS, SANE and Pittsburgh scores showed statistical improvement after the injection (P < .01). Specifically, the improvement in the ASES score which was the primary outcome measure was significantly greater in the group without tears than in the group with PTRCTs at all follow-up times. Moreover, 94% of the patients in the isolated RCT group and 49% in the PTRCTs group achieved a substantial clinical benefit at 12 months follow up. Ten out of the 50 patients (20%) who received PRP injections due to a partial RC tear underwent surgery due to lack of clinical improvement.

Conclusions

Subacromial PRP injections produced a significant improvement in, shoulder function, pain and sleep disturbances in most patients with RCT refractory to conservative treatment that was maintained up to 12-month follow-up. Moreover, most patients returned to sports at the same level they had previous to the injury. However, improvement in symptoms and functional outcomes were significantly worse in patients who had a PTRCT compared with patients who had an isolated tendinopathy.
Level of Evidence: Prospective Cohort study, Level of evidence II