ISAKOS: 2019 Congress in Cancun, Mexico

2019 ISAKOS Biennial Congress ePoster #709


The Use of the Bi-Component Carboxymethylcelulos-Polysaccarid B in the Knee Joint During ACL Reconstruction

Diego C. Astur, MD, PhD, São Paulo, SP BRAZIL
Renan M. Chaim, São Paulo, SP BRAZIL
Felipe C. Baras, MD, Winnipeg, Manitoba CANADA
Alexandre P. Nicolini, MD, MSc, São Paulo, SP BRAZIL
Henrique B. Freire de Carvalho, São Paulo, SP BRAZIL
Moises Cohen, MD, PhD, Prof., São Paulo, SP BRAZIL

Universidade Federal de São Paulo, São Paulo, SP, BRAZIL

FDA Status Not Applicable





Postoperative complications in ACL(anterior cruciate ligament) reconstruction may occur. Among them, the most common is arthrofibrosis, with rates varying from 4 to 38% in the literature. Edema and postoperative inflammation are among the causes. The bi-component carboxyethylcellulose-polymer B is a natural product that acts as a hemostatic and a non-stick barrier. Purpose: The aim of this study was to evaluate the use of intra – articular carboxymethylcellulose - B polysaccharide in the reconstruction of the ACL. Methods: We performed a prospective randomized clinical trial: 30 patients were divided into 2 groups of 15 patients. In the first (control) the aspiration of the saline solution was performed at the end of the surgical procedure. In the second one (intervention) the intra - articular bi - component was applied to the final of ACL reconstruction surgery. We assessed postoperative pain on the first, third, fifth and seventh postoperative days; edema and range of motion(ROM) were assessed on the first and seventh day. Results: The intervention group presented less pain in the third (p = 0.017) and fifth (p = 0.029) postoperative day when compared to the control group. There was also regression of edema in relation to group 1 on the first surgical day (p = 0.001), as well as a decrease in edema between the first and seventh postoperative days in group 2 (p = 0.041). There was also an improvement in ROM in patients in group 2 superior to patients in group 1 after seven days of surgery (p = 0.008). Conclusion: The efficacy of the bi-component in pain control in relation to the control group (third and fifth days), improvement of edema on the first day, and faster regression between the first and seventh day and better movement on the seventh postoperative day, demonstrates the benefit of the compound in an early rehabilitation, fundamental for a satisfactory surgical result.