2019 ISAKOS Biennial Congress ePoster #1042
Survivorship after Meniscal Allograft Transplantation According to Articular Cartilage Status
Jun-Gu Park, MD, Seoul KOREA, REPUBLIC OF
Seong-Il Bin, MD, PhD, Seoul KOREA, REPUBLIC OF
Sung-Mok Oh, MD, Seoul KOREA, REPUBLIC OF
Bum-Sik Lee, MD, Seoul KOREA, REPUBLIC OF
Jong-Min Kim, MD, PhD, Seoul KOREA, REPUBLIC OF
Tae-Hyuk Kim, MD, Seoul KOREA, REPUBLIC OF
Dept. of Orthopaedic Surgery, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, KOREA, REPUBLIC OF
FDA Status Not Applicable
Our findings showed that MAT was an effective symptomatic treatment in knees with advanced bipolar chondral lesions.
Clinical outcomes after meniscal allograft transplantation (MAT) in arthritic knees are unclear, and objective estimates of graft survival according to the articular cartilage status have not been performed.
MAT should provide clinical benefits in knees with high-grade cartilage damage, but their graft survivorship should be inferior to that in knees with low-grade chondral degeneration after MAT.
The records of 222 patients who underwent primary MAT were reviewed. The patients were grouped according to the degree and location of articular cartilage degeneration: low-grade chondral lesions (International Cartilage Repair Society [ICRS] grade =2) on both the femoral and tibial sides (ideal indication), high-grade lesions (ICRS grade 3 or 4) on either the femoral or tibial side (relative indication), and high-grade lesions on both sides (salvage indication). Kaplan-Meier survival analysis with the log-rank test was performed Results
The mean (±SD) Lysholm score significantly improved from 63.1 ± 15.1 to 85.1 ± 14.3 (P<.001). However, the postoperative scores were not significantly different between the 3 groups (P = .877). The estimated cumulative graft survival rate at 5 years in the salvage indication group (62.2% [95% CI, 41.6-82.8]) was significantly lower than that in the other 2 groups (ideal indication: 93.8% [95% CI, 88.5-99.1]; relative indication: 90.9% [95% CI,81.1-100.0]) (P = .006).
Our findings showed that MAT was an effective symptomatic treatment in knees with advanced bipolar chondral lesions. However, better graft survival can be expected when articular cartilage is intact or if chondral damage is limited to a unipolar lesion.